High Serum Interleukin-10 and Tumor Necrosis Factor Alpha Levels in Chronic Paracoccidioidomycosis

M. Fornari, A. Bava, M. Guereño, V. Berardi, M. R. Silaf, R. Negroni, R. Diez
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引用次数: 33

Abstract

ABSTRACT In patients with chronic paracoccidioidomycosis (n= 10), levels of tumor necrosis factor alpha, interleukin-10, and interleukin-2 in serum, measured by enzyme-linked immunosorbent assay (in picograms per milliliter, as mean ± standard error of the mean), were higher than in normal controls (n = 8): 186 ± 40 versus 40 ± 7 (P < 0.05), 203 ± 95 versus 20 ± 8 (P = 0.001), and 96.3 ± 78.57 versus 1.19 ± 1.19 (P = 0.045), respectively. Gamma interferon and interleukin-4 levels were similar in patients and controls.
慢性副球孢子菌病患者血清白细胞介素-10和肿瘤坏死因子α水平升高
文摘患者慢性paracoccidioidomycosis (n = 10),肿瘤坏死因子-α水平,白细胞介素- 10”,和血清中白介素2,以酶联免疫吸附试验(在每毫升皮克,平均值±标准平均误差),均高于正常对照组(n = 8): 186±40和40±7 (P < 0.05), 203±95和20±8 (P = 0.001),和96.3±78.57和1.19±1.19 (P = 0.045),分别。患者和对照组的γ干扰素和白细胞介素-4水平相似。
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