Rethinking for Natural Pharmaceutical Technology: Parabens as Cosmetic Preservatives and their Potential as Chemical Endocrine Disruptors

Sesto Cabral Maria Eugenia, González Elías Exequiel, Moreno Maria Julieta
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Abstract

The movement of conscious consumption is growing rapidly. The idea of leaving behind synthetic products and substances that generate waste from their production to their final disposal grows and widens the gap between the old capitalist paradigm and the concept of naturism. It includes environmental awareness, taking care of our body, and the conscious choice of what we eat, wear, and use in daily life, including cosmetic products. This study aimed to explore a new paradigm of formulation and consumption. A group of parabens was selected, and their replacement with preservatives approved for natural cosmetics was proposed. Some of the risks associated with the consumption of parabens in food, cosmetics, and medicines, were also examined. Moreover, the advantages and disadvantages of preservatives for the product and consumer were also discussed. For data collection, publications in indexed journals were searched, with the keywords: parabens, endocrine disrupting chemicals, and skin conditions related to the use of parabens. Recent studies have reported that by using parabens in skin products, we create an imbalance in the skin flora. This preservative decreases the defense capacity of our first immune line and causes disorders that lead to irritation, rosacea spots, oiliness, and sectorized peeling. Furthermore, parabens are exogenous substances that alter the functions of the endocrine system and can cause adverse health effects. In Argentina, compounds from the paraben family are used by many brands as preservatives, which are dangerous to health and the environment. Therefore, a conscious, sustainable, biodegradable, and cruelty-free alternative is needed to replace parabens in cosmetics
对天然制药技术的反思:对羟基苯甲酸酯作为化妆品防腐剂及其作为化学内分泌干扰物的潜力
自觉消费运动迅速发展。抛弃从生产到最终处理产生废物的合成产品和物质的想法日益增长,并扩大了旧资本主义范式和自然主义概念之间的差距。它包括环保意识,照顾我们的身体,以及我们在日常生活中吃、穿和使用的有意识的选择,包括化妆品。本研究旨在探索一种新的配方与消费模式。选择了一组对羟基苯甲酸酯,并建议用天然化妆品批准的防腐剂替代它们。还研究了在食品、化妆品和药品中使用对羟基苯甲酸酯的一些风险。此外,还讨论了防腐剂对产品和消费者的利弊。为了收集数据,检索了索引期刊上的出版物,关键词是:对羟基苯甲酸酯、内分泌干扰化学物质和与使用对羟基苯甲酸酯相关的皮肤状况。最近的研究报告说,在皮肤产品中使用对羟基苯甲酸酯,我们造成了皮肤菌群的不平衡。这种防腐剂会降低我们第一免疫系统的防御能力,导致皮肤紊乱,导致刺激、酒渣鼻斑点、出油和部分脱皮。此外,对羟基苯甲酸酯是外源性物质,可改变内分泌系统的功能,对健康造成不利影响。在阿根廷,许多品牌使用对羟基苯甲酸酯类化合物作为防腐剂,这对健康和环境都是有害的。因此,需要一种有意识的、可持续的、可生物降解的、无残忍的替代品来取代化妆品中的对羟基苯甲酸酯
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