Impact of applying albendazole and Levamisole against some intestinal parasites in fish

Abstract

T he continuous search for more effective therapeutic strategies and drugs to overcome the fishs' intestinal parasites was an incentive to carry out this study in the context of drug resistance and because of parasitic diversity in both Oreochromis niloticus and Clarias garpeinus leading to economic problems. Two stages have been implemented to evaluate the therapeutic effect of the most used anthelmintic drugs albendazole, and levamisole. The survey of some fish farms for internal parasites was applied on 320 fish as a first stage. The parasitological examinations were applied on fish fecal matter including physical examination and clinical signs. pathological investigation in companion with parasitological one was executed on 50 positive fish obtained from positive cases previously examined. Sixty-six infected fish from first stage were transported to the second stage which is experimental by divided it into groups compared with non-infected fish. Full pathological, hematological and biochemical studies on experimental fish were executed. Our results of first stage were exhibited total-ly116 positive cases with prevalence (116/320) 36.25% of infestation with intestinal parasites. Five helminth parasites represented by cestode, nematode and trematode were isolated from total 50 dissected fish. The results of second stage were in favor of the treated groups showed marked improvement while both antiparasitic drugs revealed nearly similar results. Full pathological, hematological and biochemical studies were introduced.