Differences of the changes in tear film with four types of artificial tear treatment on dry eye after phacoemulsification

中国实用眼科杂志 Pub Date : 2017-09-10 DOI:10.3760/CMA.J.ISSN.1006-4443.2017.09.014

Qiu-jian Zhu, Xiao-ying Xing, Zuo-hong Wu, Ding Chen

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Abstract

Objective To study the difference of the tear film changes of four types artificial tear in treatment of dry eye after phacoemulsification by spectral-domain OCT (SD-OCT). Methods This clinical study included 40 patients (40 eyes) having dry eye after phacoemulsification, 10 patients used Tears Naturale Forte Eye Drops (group A), 10 patients used Polyethylene Glycol Eye Drops (group B), 10 patients used Sodium Hyaluronate Eye Drops (group C), 10 patients used Carboxxymethylcellulose Sodium Eye Drop (group D). Total tear meniscus area (TTMA) was measured before and at differeat times after treatment. Results In the group A and B, TTMA was statistically significantly (P <0.05) better than preoperatively at 0 minute, 10 minute, 20 minute, 30 min-ute and 45 minute. In the group C and D, TTMA was statistically significantly (P <0.05) better than preoperatively at 0 minute and 10 minute. Comparison among groups, at 10 minute, TTMA of group B was statistically significantly (P=0.020, P=0.011) better than group C and group D. At 20 minute TT-MA of group A and group B was statistically significantly (P=0.006, P=0.005, P=0.004, P=0.003) better than group C and group D. Even at 45minute, TTMA of group B was statistically significantly (P=0.040, P=0.016) better than group C and group D. Conclusions Polyethylene Glycol Eye Drops and Tears Naturale Forte Eye Drops are better in treatment of dry eye after phacoemulsification, and q1h is recommended. Key words: Artificial tear; Cataract; Tear meniscus; OCT

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四种人工泪液处理对超声乳化术后干眼泪膜变化的影响

目的研究超声乳化术后4种人工泪液在干眼治疗中的泪膜变化差异。方法选取超声乳化术后干眼患者40例(40只眼)，采用天然强光滴眼液10例(A组)，聚乙二醇滴眼液10例(B组)，透明质酸钠滴眼液10例(C组)，羧甲基纤维素钠滴眼液10例(D组)，测定治疗前后不同时间的泪液半月板总面积(TTMA)。结果A、B组患者在0分钟、10分钟、20分钟、30分钟、45分钟时TTMA均优于术前，差异均有统计学意义(P <0.05)。C、D组患者0分钟、10分钟TTMA优于术前，差异均有统计学意义(P <0.05)。组间比较，10 min时，B组TTMA优于C组和d组，差异均有统计学意义(P=0.020, P=0.011)。20 min时，A组和B组TT-MA优于C组和d组，差异均有统计学意义(P=0.006, P=0.005, P=0.004, P=0.003)。45min时，B组TTMA优于C组和d组，差异均有统计学意义(P=0.040，P=0.016)优于C组和d组。结论聚乙二醇滴眼液和天然强光滴眼液治疗超声乳化术后干眼症效果较好，推荐使用q1h。关键词:人工泪液;白内障;半月板撕裂;10月

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中国实用眼科杂志

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期刊介绍： China Practical Ophthalmology was founded in May 1983. It is supervised by the National Health Commission of the People's Republic of China, sponsored by the Chinese Medical Association and China Medical University, and publicly distributed at home and abroad. It is a national-level excellent core academic journal of comprehensive ophthalmology and a series of journals of the Chinese Medical Association. China Practical Ophthalmology aims to guide and improve the theoretical level and actual clinical diagnosis and treatment ability of frontline ophthalmologists in my country. It is characterized by close integration with clinical practice, and timely publishes academic articles and scientific research results with high practical value to clinicians, so that readers can understand and use them, improve the theoretical level and diagnosis and treatment ability of ophthalmologists, help and support their innovative development, and is deeply welcomed and loved by ophthalmologists and readers.