Evaluation of the Relationship Between Perfusion Index and the Improvement of Patent Ductus Arteriosus

IF 0.4 4区医学 Q4 PEDIATRICS

Iranian Journal of Pediatrics Pub Date : 2023-02-28 DOI:10.5812/ijp-134709

Razieh Sangsari, Hosein Dalili, M. Kadivar, M. Saeedi, K. Mirnia, Azam Fathi, Javad Hakimelahi

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引用次数: 0

Abstract

Background: Patent ductus arteriosus (PDA) is a disease presenting on the first days of birth, associated with unpleasant complications such as exaggerated respiratory distress and increased mortality, requiring prompt treatment. Objectives: This study evaluated the relationship between perfusion index and the recovery of patients diagnosed with PDA. Methods: In this cross-sectional study, 22 neonates with PDA (as the case group) and 22 healthy neonates (as the control group) were selected. The difference in perfusion index (PI) before and after arterial duct closing was determined, and also the relationship between pre-ductal and post-ductal PI in the case and control groups was evaluated. Data were analyzed by SPSS version 21. Results: The results showed a significant difference in the mean scores of pre-ductal and post-ductal PI before and after arterial duct closure (P = 0.004). Also, pre-ductal and post-ductal PI scores were significantly lower in the case group than in the control group (P < 0.001) Conclusions: According to our findings, PI in infants with PDA is low at presentation and increases after treatment. Therefore, PI can be used as an indicator to evaluate response to treatment during follow-up, particularly when repeated echocardiography is not accessible.

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血流灌注指数与动脉导管未闭改善关系的评价

背景:动脉导管未闭(PDA)是一种出现在出生第一天的疾病，伴有令人不快的并发症，如呼吸窘迫加重和死亡率增加，需要及时治疗。目的:探讨灌注指数与PDA患者恢复的关系。方法:采用横断面研究方法，选取患有PDA的新生儿22例作为病例组，健康新生儿22例作为对照组。测定动脉导管闭合前后灌注指数(PI)的差异，并评价病例组与对照组导管前、导管后PI的关系。数据采用SPSS version 21进行分析。结果:动脉导管闭合前后导管前、导管后PI平均评分差异有统计学意义(P = 0.004)。此外，病例组的导管前和导管后PI评分明显低于对照组(P < 0.001)。结论:根据我们的研究结果，PDA患儿的PI在发病时较低，治疗后升高。因此，PI可以作为随访期间评估治疗反应的指标，特别是在无法获得重复超声心动图的情况下。

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来源期刊

Iranian Journal of Pediatrics 医学-小儿科

CiteScore

0.90

自引率

20.00%

发文量

审稿时长

6-12 weeks

期刊介绍： Iranian Journal of Pediatrics (Iran J Pediatr) is a peer-reviewed medical publication. The purpose of Iran J Pediatr is to increase knowledge, stimulate research in all fields of Pediatrics, and promote better management of pediatric patients. To achieve the goals, the journal publishes basic, biomedical, and clinical investigations on prevalent diseases relevant to pediatrics. The acceptance criteria for all papers are the quality and originality of the research and their significance to our readership. Except where otherwise stated, manuscripts are peer-reviewed by minimum three anonymous reviewers. The Editorial Board reserves the right to refuse any material for publication and advises that authors should retain copies of submitted manuscripts and correspondence as the material cannot be returned. Final acceptance or rejection rests with the Editors.