Features of Neurovascular Orofacial Pain Compared to Painful Posttraumatic Trigeminal Neuropathy.

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2020-04-01 DOI:10.11607/ofph.2448

Y. Haviv, A. Zini, N. Keshet, G. Almoznino, R. Benoliel, Y. Sharav

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引用次数: 10

Abstract

AIMS To test and re-examine the diagnostic criteria for neurovascular orofacial pain (NVOP) compared to posttraumatic trigeminal neuropathy (PTTN). METHODS Pain and patient characteristics were compared in patients with NVOP, PTTN, and NVOP initiated by trauma (PT-NVOP). NVOP criteria were based on prior studies, and PTTN was defined according to the International Classification of Headache Disorders, version 3 beta. RESULTS Of the 170 patients in the cohort, 90 had PTTN, 51 had NVOP, and 29 had PT-NVOP. None of the tested parameters in the NVOP and PT-NVOP patients were significantly different, and therefore these patients were combined into one group (T-NVOP). T-NVOP differed significantly from PTTN (P < .001) in periodic pain patterns, presence of autonomic and systemic signs, throbbing pain quality, and frequency of bilaterality. Pain quality in PTTN was more burning/stabbing than in NVOP (P = .003). Pain severity, waking from sleep, muscle sensitivity to palpation, and demographics were comparable. CONCLUSION NVOP differs from PTTN in parameters essential to diagnosis: periodicity of pain, presence of autonomic and systemic accompanying signs, throbbing pain quality, and bilateral presentation. NVOP is amenable to abortive and prophylactic antimigraine therapies, distinguishing NVOP from PTTN in clinical features, treatment, and prognosis.

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神经血管性口面部疼痛与创伤后疼痛性三叉神经病变的特征比较。

目的探讨神经血管性口面痛(NVOP)与创伤后三叉神经病变(PTTN)的诊断标准。方法比较NVOP、PTTN和外伤引发的NVOP (PT-NVOP)患者的西班牙和患者特征。NVOP的标准是基于先前的研究，而PTTN是根据国际头痛疾病分类第3版beta版定义的。结果170例患者中，90例为PTTN, 51例为NVOP, 29例为PT-NVOP。NVOP和PT-NVOP患者的各项检测参数均无显著差异，故将其合并为一组(T-NVOP)。T-NVOP与PTTN在周期性疼痛模式、自主神经和全身体征、悸动疼痛质量和双侧频率方面有显著差异(P < 0.001)。PTTN患者的疼痛质量比NVOP患者更灼烧/刺痛(P = 0.003)。疼痛严重程度，从睡眠中醒来，肌肉触诊敏感性和人口统计学具有可比性。结论nvop与PTTN的诊断参数不同:疼痛的周期性、自主和全身伴随症状、悸动性疼痛的质量和双侧表现。NVOP可接受流产和预防性抗偏头痛治疗，在临床特征、治疗和预后上将NVOP与PTTN区分开来。

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.