The effect of drug information service using leaflet media and medication reminder chart on adherence and blood pressure of hypertensive patients in primary health care

Yopi Rikmasari
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Abstract

Abstract Background: Treatment adherence is an important factor affecting blood pressure control in hypertensive patients. Intervention in pharmacy service can improve medication adherence and lower blood pressure. Objective: This study aimed to evaluate the effect of drug information service using leaflets and MRC on the level of patient compliance and lowering blood pressure. Method: The research design was a quasi-experimental pre-and post-design with control, the intervention group (n=20), and the control group (n=20). The patient adherence was measured using the MGLS questionnaire at the beginning and the end of the study. The intervention was performed by distributing a drug information leaflet and medication reminder chart (MRC). The differences of adherence pre and post-intervention were analyzed using paired t-test, while the differences in adherence and blood pressure between the control and the intervention group were analyzed using the Mann-Whitney test. Results: The results showed that there was a significant difference in adherence between pre and post-intervention (p<0.001). A significant difference was also found in the level of adherence between the control group and the intervention group (p<0.001). Whereas the decrease of systolic (p=0.396) and diastolic (p=0.564) blood pressure in the intervention group and control group was not different significantly. Conclusion: Drug information services using leaflets and MRCs affected patient adherence to medication, but did not interfere with the decrease of systolic and diastolic blood pressure. Keywords: leaflets, medication reminder chart, adherence, blood pressure
单张媒介和用药提醒表等药物信息服务对高血压患者依从性和血压的影响
背景:治疗依从性是影响高血压患者血压控制的重要因素。干预药房服务可提高服药依从性,降低血压。目的:探讨单张药品信息服务和MRC对患者依从性和降压的影响。方法:采用准实验前后设计,对照组、干预组(n=20)、对照组(n=20)。在研究开始和结束时使用MGLS问卷测量患者的依从性。通过分发药物信息单张和药物提醒表(MRC)进行干预。干预前后依从性差异采用配对t检验分析,对照组与干预组依从性、血压差异采用Mann-Whitney检验分析。结果:干预前后依从性差异有统计学意义(p<0.001)。对照组和干预组的依从性水平也有显著差异(p<0.001)。而干预组与对照组的收缩压(p=0.396)、舒张压(p=0.564)下降无显著差异。结论:使用单张和MRCs的药物信息服务影响患者对药物的依从性,但不影响收缩压和舒张压的降低。关键词:传单,用药提醒表,依从性,血压
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