“FTIR, Uv- Vis And GCMS Analysis Of Potential Bioactive Compounds From Tinospora Cordifolia And Its Antibacterial Activity”

Abstract

: Medicinal plants are assuming greater importance in the primary health care of individuals and communities in many developing countries. Endophytes are the microorganisms inhabiting the living tissues of plants. Endophytic fungi from medicinal plants have created a huge potential in generating novel drugs. The secondary metabolites and their semi-synthetic derivatives play an important role in anticancer drug therapy. The present study is investigated for the isolation of endophytes from the inner bark of twigs and leaves of Tinospora cordifolia , collected from the Shankaraghatta regions, Shivamogga district of Karnataka and examined as a potential source of anticancer drug lead compound. Bioactive components of Tinospora cordifolia have been evaluated using GCMS, UV-VIS and FTIR and its antibacterial activity. GC-MS analysis revealed the chemical profile of extract of different compound, distinct peak, retention time (RT), molecular formula, molecular weight (MW) and chemical structure. The GC–MS analysis of methanol extracts detected the presence of 30 phytochemical compounds. The UV-VIS profile showed the presence of peaks at 190-500nm revealing the presence of secondary metabolites in T. cordifolia . The results of FTIR analysis confirmed the presence of phenol, alkanes, alkenes, alcohol, aromatic, aliphatic amines and amine compound. The results show that important bioactive compounds present in plant extract and these constituents may be responsible for pharmacological activities.