Resected metachronous renal metastasis of pancreatic cancer after pancreaticoduodenectomy—a case report

Abstract

: Majority of patients experience recurrence of pancreatic cancer after pancreatectomy which results in poor prognosis. This is an initial report on a patient with resected solitary renal metastasis from pancreatic cancer. The case was a 58-year-old man who underwent pancreaticoduodenectomy for pancreatic cancer. He was on S1 treatment as adjuvant chemotherapy, where 10 mm left renal nodule was detected 9 months after primary resection. The renal nodule increased to 15 mm in 2 months, although there were no increase in tumor markers. Nephrectomy revealed that the pathological diagnosis was adenocarcinoma of pancreatic origin. No definite evidence of recurrence was observed with gemcitabine treatment for 10 months after nephrectomy. When a renal mass is newly detected in the post-operative course of pancreatic cancer, renal metastasis should be considered as a differential diagnosis. Among the multidisciplinary treatments, aggressive surgery for solitary renal metastasis may contribute to better survival in selected patients.