Molecular signaling pathways and cancer pain in gastric cancer

Abstract

The molecular signaling pathways in gastric cancer, such as mitogen-activated protein kinase, phosphoinoinositide 3-kinase/protein kinase B, AMP-activated protein kinase, cyclooxygenase 2/nuclear factor-κB and Wnt/β-catenin pathways are closely related to the occurrence and development of cancer pain. To understand the expression and role of gastric cancer molecular signaling pathway in cancer pain is expected to provide a new idea for the treatment of cancer pain. Key words: Stomach neoplasms; Cancer pain; Signaling pathway