Seroprevalence of and risk factors for Leishmania seropositivity in a sample population of Western Sicily (Italy)

Q3 Nursing

Epidemiology Biostatistics and Public Health Pub Date : 2022-06-16 DOI:10.2427/9024

E. Amodio, G. Calamusa, E. Sidoti, A. Migliazzo, F. Vitale, C. Costantino, F. Vitale

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引用次数: 1

Abstract

Background: Leishmania is a vector-borne parasite responsible for significant morbidity and mortality worldwide. The aim of this study was to assess the prevalence of and risk factors for Leishmania infantum seropositivity in a sample of Sicilian population.Methods: A total of 260 subjects were interviewed using a standardized questionnaire and requested for an venous blood sample.Results: Overall, 36 subjects (13.8%) were seropositive against L. infantum with a statistically significant higher prevalence of positivity in older subjects (p=0.04). After adjustment for age, a higher risk for Leishmania seropositivity was found in subjects who had pets living outdoors and untreated with anti-pests, and in those who were current smokers (adj-OR = 2.95 and adj-OR = 3.11, respectively; p < 0.05).Conclusions: Our data confirm that Leishmania infections among Sicilian citizens can be considered relatively frequent, suggesting that a percentage of Leishmania seropositivity can be probably attributed to exposure to both old and new risk factors.

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西西西里岛(意大利)样本人群利什曼原虫血清阳性率及血清阳性危险因素分析

背景:利什曼原虫是一种媒介传播的寄生虫，在世界范围内造成严重的发病率和死亡率。本研究的目的是评估西西里岛人群样本中婴儿利什曼原虫血清阳性的患病率和危险因素。方法:采用标准化问卷对260名受试者进行访谈，并采集静脉血。结果:总体而言，36名受试者(13.8%)的婴儿乳杆菌血清阳性，其中年龄较大的受试者阳性率较高(p=0.04)。经年龄调整后，有宠物在户外生活且未进行抗虫治疗的受试者，以及目前吸烟的受试者，利什曼原虫血清阳性的风险更高(adjo = 2.95和adjo = 3.11);P < 0.05)。结论:我们的数据证实，西西里公民中的利什曼原虫感染可以被认为是相对频繁的，这表明利什曼原虫血清阳性的百分比可能归因于暴露于新旧危险因素。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Epidemiology Biostatistics and Public Health PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-

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期刊介绍： Epidemiology, Biostatistics, and Public Health (EBPH) is a multidisciplinary journal that has two broad aims: -To support the international public health community with publications on health service research, health care management, health policy, and health economics. -To strengthen the evidences on effective preventive interventions. -To advance public health methods, including biostatistics and epidemiology. EBPH welcomes submissions on all public health issues (including topics like eHealth, big data, personalized prevention, epidemiology and risk factors of chronic and infectious diseases); on basic and applied research in epidemiology; and in biostatistics methodology. Primary studies, systematic reviews, and meta-analyses are all welcome, as are research protocols for observational and experimental studies. EBPH aims to be a cross-discipline, international forum for scientific integration and evidence-based policymaking, combining the methodological aspects of epidemiology, biostatistics, and public health research with their practical applications.