{"title":"Effect of Wasabi on Ion Secretion in Guinea Pig Colon.","authors":"H. Nakayama, Toshihiro Suzuki, Yuichi Suzuki","doi":"10.1271/NOGEIKAGAKU1924.72.499","DOIUrl":null,"url":null,"abstract":"ワサビ茎エーテル抽出残渣水溶性画分は, 5-HT投与および電気的フィールド刺激によるCl-分泌活性を抑制した.また, TTX存在下ではBChによるCl-分泌活性を抑制し,その抑制効果はindomethacin存在下では消失した.さらに,粘膜標本において, TTXおよびindomethacin存在下で, forskolinとBChによるCl-分泌活性に影響しなかった.これらのことから,ワサビ茎抽出物は,粘膜上皮細胞には直接作用せず,粘膜下神経叢およびprostaglandin類産生機構などに作用して, Cl-分泌活性を抑制していると考えられる.","PeriodicalId":9443,"journal":{"name":"Bulletin of the Agricultural Chemical Society of Japan","volume":"23 1","pages":"499-507"},"PeriodicalIF":0.0000,"publicationDate":"1998-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"2","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Bulletin of the Agricultural Chemical Society of Japan","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1271/NOGEIKAGAKU1924.72.499","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}