Effect of strain difference on lipid metabolism in rats after an acute ethanol administration

S. Mochizuki, A. Yoshida
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引用次数: 3

Abstract

effect of some dietary components on fatty liver by using a model of the fatty liver induced by acute ethanol administration. We often observed no or only a slight lipid accumulation in the liver, even when we administered ethanol by the method reported in the previous paper.1} Wesupposed that one of the reasons might be due to the breeder and/or strain differences in the rats. Male Sprague-Dawley (SD) rats at 5 weeks of age were obtained from Charles River Japan (Kanagawa), Nihon Clea (Tokyo), Nihon SLC (Shizuoka), and Seiwa
品系差异对急性乙醇给药后大鼠脂质代谢的影响
采用急性乙醇致脂肪肝模型,研究几种饲料成分对脂肪肝的影响。我们经常观察到肝脏中没有或只有轻微的脂质积累,即使我们用前一篇论文中报道的方法给药乙醇。我们推测其中一个原因可能是由于繁殖者和/或大鼠的品系差异。5周龄雄性Sprague-Dawley (SD)大鼠分别来自日本神奈川Charles River、东京Nihon Clea、静冈Nihon SLC和Seiwa
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