Gifts from Chinese Medicine for diabetic nephropathy: Ancient formulas in modern times

2012 IEEE International Conference on Bioinformatics and Biomedicine Workshops Pub Date : 2012-10-04 DOI:10.1109/BIBMW.2012.6470374

Lei Zhang, W. Mao, Yin Li, G. Su, Xusheng Liu

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Abstract

To provide inspiration for developing new therapies of diabetic nephropathy, our study combed ancient formulas for diabetic nephropathy recorded in China from Tang dynasty to Qing dynasty, and discussed their application in modern times. A total of 87 ancient formulas for diabetic nephropathy were collected. Six-Ingredient Rehmannia Pill and Supplemented Kidney Qi Pill were recorded at higher frequency. Radix Astragali liqid, Xuan Bu Pill, and Ass Hide Glue Decoction were the earliest formulas for diabetic nephropathy recorded in Tang dynasty. Ginseng Powder was recorded by doctors in 4 dynasties, with the highest dynastic repeated frequency. Only formulas with high recorded frequency, such as Six-Ingredient Rehmannia Pill, Supplemented Kidney Qi Pill, Poria Pill, Four Ingredients Decoction, Pilose Antler Pill, were applied or studied in modern times keeping original medicinal combination. Most ancient formulas have not been made good use, and just sovereign medicinals in them were applied. In order to have better guidance from valuable experiences in ancient China, we should pay more attention to apply and study ancient formulas with original combination, not only the single Chinese medicinal.

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中医药馈赠糖尿病肾病:现代古方

为了给糖尿病肾病新疗法的开发提供启示，本研究对中国唐代至清代的糖尿病肾病古方进行了梳理，并探讨了其在现代的应用。共收集糖尿病肾病古方87种。六味地黄丸和补肾益气丸出现频率较高。黄芪液、宣补丸、驴皮胶汤是唐代记载最早的糖尿病肾病方剂。参粉有4朝医生记载，朝代重复频率最高。近代仅应用或研究六味地黄丸、补肾益气丸、茯苓丸、四味汤、鹿茸丸等记录频率较高的方剂，保持原有的用药组合。大多数古代配方都没有得到很好的利用，只是在其中应用了主权药物。为了从中国古代的宝贵经验中得到更好的指导，我们应该更多地注意应用和研究具有原始组合的古代方剂，而不仅仅是单一的中药。

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2012 IEEE International Conference on Bioinformatics and Biomedicine Workshops

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