Synthesis and Reactions of 3-(2-Chloromethyl-carbonylamino)tetrachloroquinazolin-2,4-dione

Organic Chemistry International Pub Date : 2012-08-13 DOI:10.1155/2012/284947

M. Hassan, A. Younes, M. Taha, Aboubakr Haredi Abdelmonsef

引用次数: 6

Abstract

A series of tetrachloroquinazolin-2,4-dione derivatives were synthesized using appropriate synthetic route and characterized by IR, 1H NMR, MS, and elemental analysis. The synthesized compounds were evaluated for their preliminary in vitro antibacterial activity towards Salmonella typhi, Staphylococcus aureus, and Bacillus cereus.

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3-(2-氯甲基-羰基氨基)四氯喹唑啉-2,4-二酮的合成与反应

采用合适的合成路线合成了一系列四氯喹唑啉-2,4-二酮衍生物，并通过IR、1H NMR、MS和元素分析对其进行了表征。对合成的化合物进行了对伤寒沙门氏菌、金黄色葡萄球菌和蜡样芽孢杆菌的初步体外抗菌活性评价。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Organic Chemistry International

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