Curative Effect of Interventional Therapy and Neurological Changes in Ischemic Stroke of Posterior Circulation Evaluated by Magnetic Resonance Imaging under Genetic Algorithm

Sci. Program. Pub Date : 2022-01-07 DOI:10.1155/2022/2656706
Xiaodu Yu, Xingyou Zheng, Daoyou Cheng
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Abstract

Objective. This study aimed to evaluate the improvement and neurological function changes of patients with ischemic stroke in the posterior circulation before and after interventional therapy using magnetic resonance imaging (MRI) under genetic algorithm and compressed sensing algorithm. Methods. Thirty-six patients with posterior circulation ischemia who visited the interventional cerebrovascular disease area were included in this study. The treatment effect was observed through abnormal signal changes in the lesion area on each sequence of MRI images before and after treatment. The National Institutes of Health Stroke Scale (NIHSS) was used for the evaluation of the changes in neurological function. Results. The real data experiment results suggested that the peak signal-to-noise ratio (PSNR) = 39.33 and structure similarity (SSIM) = 0.96 in the algorithm reconstructed image, which showed no significant difference with the simulation experiment results of PSNR = 35.19 and SSIM = 0.96 ( P < 0.05 ). In addition, the stenosis rate after interventional treatment (13.89%) was substantially lower than that before treatment (91.67%) ( P < 0.05 ). Cerebral blood flow (CBF) of the bilateral occipital lobes and cerebellum after six months of treatment was higher than that before treatment ( P < 0.05 ), and the incidence of postoperative restenosis was 11.11% (4/36). Conclusion. The combination of genetic algorithm and compressed sensing algorithm had a good effect on MRI image processing. The posterior circulation ischemia interventional stent implantation can effectively improve the stenosis of the vertebral artery and vertebral basilar artery as well as the cerebral tissue perfusion in the ischemic area, which improved the clinical symptoms substantially and reduced the probability of restenosis.
遗传算法下磁共振成像评价介入治疗后循环缺血性卒中的疗效及神经功能改变
目标。本研究旨在评价遗传算法和压缩感知算法下磁共振成像(MRI)对缺血性卒中患者介入治疗前后后循环的改善和神经功能的改变。方法。本研究纳入36例后脑循环缺血的介入脑血管病患者。通过治疗前后各序列MRI图像病变区域异常信号变化观察治疗效果。采用美国国立卫生研究院卒中量表(NIHSS)评估神经功能的变化。结果。真实数据实验结果表明,算法重构图像的峰值信噪比(PSNR) = 39.33,结构相似度(SSIM) = 0.96,与模拟实验结果PSNR = 35.19, SSIM = 0.96无显著差异(P < 0.05)。此外,介入治疗后狭窄率(13.89%)明显低于治疗前(91.67%)(P < 0.05)。治疗6个月后双侧枕叶和小脑脑血流量(CBF)高于治疗前(P < 0.05),术后再狭窄发生率为11.11%(4/36)。结论。遗传算法与压缩感知算法的结合在MRI图像处理中取得了良好的效果。后循环缺血介入支架植入术可有效改善椎动脉和椎基底动脉狭窄,改善缺血区脑组织灌注,显著改善临床症状,降低再狭窄的发生概率。
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