Analytical review of methods for the determination of nitrogen oxides in tobacco and nicotine containing products

Abstract

Reducing the toxicity of tobacco products is a pressing issue today. Manufacturers offer consumers innovative types of nicotine containing products, such as electric tobacco heating systems, as an alternative to traditional cigarettes. This type of nicotine containing products differs from cigarettes, i.e. the ECNT has a different way of consumption, which is the formation of the dispersed phase, which consists of the smallest solid particles in the absence of combustion by heating the filler. The presence of innovative products requires on the market evaluating and monitoring the quality of products, therefore, it is necessary to develop or improve existing methods to identify potentially harmful components for the body, including nitrogen oxides (NO, NOx), which are part of the generated aerosol. This paper presents a characteristic of nitrogen oxides (NO, NOx), reviews the formation process, toxic properties affecting the body, as well as an overview of the methods for determining nitrogen oxides using a smoking machine and chemiluminescent gas analyzer. The level of nitrogen oxides content (NO, NOx) in the gaseous phase of tobacco products aerosol compared with the content of nitrogen oxides in the gaseous phase of tobacco smoke of control cigarette 3R4F is also given. Particular attention is paid to the consideration of regulatory documentation for the regulation of innovative products. There is no generally accepted approach in the sphere of standard setting for regulation of innovative nicotine containing products at the present time and it is under development. The article substantiates the need to develop and implement in the national standard for tobacco heated methodology for determining nitrogen oxides.