Improving a self-powered glucose biosensor system using a microfluidic design

Abstract

A self-powered glucose sensor (SPGS) system integrates a biofuel cell (BFC) as a power source for operation of a biosensor. SPGS uses glucose as an analyte to be quantified and as a fuel, since it’s a molecule of biomedical interest because it’s related to diabetes. Glucose oxidase electrode-based was used in the anode and laccase based-electrode was used in the cathode within a microfluidic device where different glucose concentrations between 0 and 10 mM were used. In the polarization and current curves were observed an increase at a higher glucose concentration, without altering its operation in the presence interferences. This result indicated an improvement in the performance of an SPGS by integrating a microfluidic device, increasing the stability, limit of detection, quantification, stability and sensitivity for the quantification of glucose through the operation of a BFC.