The Gut Feeling of the Joints: Celiac Disease and Rheumatoid Arthritis Are Related

Abstract

The “mosaic of autoimmunity” is a complex, multiple-faceted, challenging scientific enigma. Celiac disease and rheumatoid arthritis are part of the autoimmune bee hive and despite being separate entities, they share multiple aspects. The present review summarizes the epidemiological, clinical, serological, genetic, environmental, enteric eco-events and associated diseases shared by the two mechanistically similar though different antigenic entities.