Crystal Structure of 1,3-Bis(p-methylphenyl)-2-flouro-1,3,2-diazaphospholidine-2-oxide

Abstract

Diazaphospholidines have the ability to bind with metals and to inhibit cholinesterase (ChE), an enzyme that has a vital role in nerve impulse transition. The crystal structure of 1,3-bis(p-methylphenyl)-2-flouro-1,3,2-diazaphospholidine-2-oxide (1) was determind using single-crystal X-ray diffraction. The five-membered ring containing phosphorus, nitrogen and carbon atoms is slightly puckered. The coordination environment around the phosphorus atom in this compound is approximately tetrahedral.