Marrium Shafi, Muhammad Akmal Khan, Yaseen Lodhi, A. Aftab, M. Sarfraz
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引用次数: 0
Abstract
Objective:
To determine the mean change in central macular thickness after cataract surgery and to compare the mean change in central macular thickness after cataract surgery in non-diabetics and diabetics without diabetic retinopathy
Study design:
Case control
Study settings and duration:
A case control study was carried out at Ophthalmology department, POF hospital, Wah Cantt. Study duration was 6 months (April 2019-September 2019)
Material and methods:
A sample size of 60 patients was calculated by using Open Epi Software. We used non probability consecutive sampling. Patients were divided into two groups; Cases (Diabetic) and controls (non-Diabetic). All patients underwent phacoemulsification and observed after 4 weeks for macular thickness measurement using optical coherence tomography before and after surgery. Data analysis was done with SPSS version 20. Post stratification t test was applied. P value ≤0.05 was considered significant.
Results:
Total 60 patients were included. Mean age of patients was 65.31 ±7. 63SD.There were 35 (58.3%) males and 25 (41.7%) female patients in the study. We found a significant increase in central macular thickness in cases and controls [(223.100±15.86SD vs 227.2667±17.9SD, p=0.000) and (221.200±12.16SD vs 226.289±16.7861SD, p =0.001)] before and after phacoemulsification in cases and controls respectively. However, no significant difference was found between the groups (p=0.486).
Conclusion:
Central macular thickness was increased after uncomplicated phacoemulsification in both diabetics and non-diabetics without retinopathy for up to a follow-up period of 4 weeks but the thickness did not differ between the two groups.
目的:确定白内障术后黄斑中央厚度的平均变化,比较非糖尿病患者和糖尿病患者白内障术后黄斑中央厚度的平均变化。研究设计:病例对照研究设置和持续时间:在华康医院POF医院眼科进行病例对照研究。研究时间为6个月(2019年4月- 2019年9月)材料和方法:使用Open Epi软件计算60例患者的样本量。我们使用非概率连续抽样。患者分为两组;病例(糖尿病)和对照组(非糖尿病)。所有患者均行超声乳化术,术后4周用光学相干断层扫描观察术前、术后黄斑厚度测量。数据分析使用SPSS version 20。采用分层后t检验。P值≤0.05为显著性。结果:共纳入60例患者。患者平均年龄65.31±7岁。63 sd。男性35例(58.3%),女性25例(41.7%)。我们发现,在超声乳化术前后,病例和对照组的中央黄斑厚度分别显著增加[(223.100±15.86SD vs 227.2667±17.9SD, p=0.000)和(221.200±12.16SD vs 226.289±16.7861SD, p= 0.001)]。但两组间无显著性差异(p=0.486)。结论:糖尿病患者和无视网膜病变的非糖尿病患者在无并发症的超声乳化术后中央黄斑厚度增加,随访时间长达4周,但厚度在两组之间没有差异。