Infertility: A product of smoke emanating from Transfluthrin coated insecticide paper (TCIP)

Toxicology Research and Application Pub Date : 2021-01-01 DOI:10.1177/23978473211025467

D. Oyeniran, A. Ojewale, P. Jewo, E. Ashamu, O. Adeniyi, S. Adelakun

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引用次数: 6

Abstract

Transfluthrin is a fast-acting insecticide used in household and hygiene products, mainly against flying insects, such as mosquito and flies, and in agriculture material pests. Its uses in these areas have not been without health risk to humans and the ecosystem. Therefore, the current study was designed to investigate the effect of smoke emanating from Transfluthrin Coated Insecticide Paper (TCIP) on adult Wistar rats’ testicular functions. The rats were grouped into three. Group A was exposed to normal environmental air. Group B and C rats were exposed via whole-body inhalation to smoke emanating from 6 g and 12 g of TCIP every day for 8 weeks. The entire groups contained eight rats each. At the end of the exposure, body and organs weight, semen analysis, biochemical assay and histological examination were evaluated and determined. The results show that the exposure significantly altered the testicular cytoarchitecture, sperm quality, hormonal profile and oxidative parameters with an increase in exposure to TCIP. This study revealed that exposure to transfluthrin is detrimental to the reproductive functions of male rats.

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不育:经氟氯菊酯涂布的杀虫纸(TCIP)产生的烟雾的产物

氟氯菊酯是一种速效杀虫剂，用于家庭和卫生用品，主要用于防治蚊子和苍蝇等飞虫以及农业物质害虫。它在这些领域的使用对人类和生态系统并非没有健康风险。因此，本研究旨在探讨经氟氯菊酯涂杀虫纸(TCIP)产生的烟雾对成年Wistar大鼠睾丸功能的影响。老鼠被分成三组。A组暴露于正常环境空气中。B组和C组大鼠每天通过全身吸入6 g和12 g TCIP产生的烟雾，持续8周。每组8只大鼠。暴露结束时，评估和测定体、器官重量、精液分析、生化化验和组织学检查。结果表明，随着TCIP暴露量的增加，睾丸细胞结构、精子质量、激素谱和氧化参数显著改变。本研究表明，暴露于氟氯菊酯对雄性大鼠的生殖功能有害。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Toxicology Research and Application

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