{"title":"Constraint Reasoning with Differential Equations","authors":"Jorge Cruz, Pedro Barahona","doi":"10.1002/anac.200310012","DOIUrl":null,"url":null,"abstract":"<p>System dynamics is naturally expressed by means of differential equations. Despite their expressive power, they are difficult to reason about and to make decisions upon, given their non-linearity and the important effects that the uncertainty on data may cause. In contrast with traditional numerical simulations that may only provide a likelihood of the results obtained, we propose a constraint reasoning framework that enables safe decision support despite data uncertainty. The approach is illustrated in the tuning of drug design and in an epidemiological study. (© 2004 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim)</p>","PeriodicalId":100108,"journal":{"name":"Applied Numerical Analysis & Computational Mathematics","volume":"1 1","pages":"140-154"},"PeriodicalIF":0.0000,"publicationDate":"2004-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/anac.200310012","citationCount":"10","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Applied Numerical Analysis & Computational Mathematics","FirstCategoryId":"1085","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/anac.200310012","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 10
Abstract
System dynamics is naturally expressed by means of differential equations. Despite their expressive power, they are difficult to reason about and to make decisions upon, given their non-linearity and the important effects that the uncertainty on data may cause. In contrast with traditional numerical simulations that may only provide a likelihood of the results obtained, we propose a constraint reasoning framework that enables safe decision support despite data uncertainty. The approach is illustrated in the tuning of drug design and in an epidemiological study. (© 2004 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim)
微分方程的约束推理
系统动力学很自然地用微分方程来表示。尽管它们的表达能力很强,但考虑到它们的非线性和数据不确定性可能造成的重要影响,很难对它们进行推理和做出决定。传统的数值模拟可能只提供获得结果的可能性,与之相反,我们提出了一个约束推理框架,尽管数据不确定,但仍能提供安全的决策支持。这种方法在药物设计的调整和流行病学研究中得到了说明。(©2004 WILEY-VCH Verlag GmbH &KGaA公司,Weinheim)
本文章由计算机程序翻译,如有差异,请以英文原文为准。