Distribution and drug susceptibility of pathogenic bacteria in 1 287 cases of neonatal dacryocystitis

Xian Li, Guizhen Zhang
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Abstract

Objective To analyze the distribution of pathogenic bacteria and drug susceptibility results in 1 287 cases of neonatal dacryocystitis in Henan Province. Methods Retrospective analysis.The pathogen culture and drug susceptibility results of 1 287 cases of dacryocystorhin in this hospital from Jan.2018 to Dec.2018 were collected. Results A total of 1 099 pathogenic bacteria were detected, and the detection rate was 85.4%.There were 618 Gram-positive bacteria strains (56.2%), included Staphylococcus aureus (19.3%), Staphylococcus epidermidis (17.5%), Streptococcus mutans (10.4%). There were 458 Gram-negative bacteria strains (41.7%), included Haemophilus influenzae (17.0%), Escherichia coli (11.5%), Klebsiella pneumoniae (7.4%). There were 23 fungi strains (2.1%). Gram-positive bacteria was the most sensitive to Vancomycin (98.8%), followed by levofloxacin (92.4%). Gram-negative bacteria was the most sensitive to imipenem (96.1%), followed by ciprofloxacin (91.4%). The resistance rate of Gram-positive bacteria and Gram-negative bacteria was the highest for erythromycin. Conclusion Gram-positive bacteria are higher than Gram-negative bacteria in the pathogenic bacteria of neonatal dacryocystitis. Key words: Dacryocystitis, neonatal; Bacteria, pathogenic; Sensitivity, drug
1 287例新生儿泪囊炎病原菌分布及药敏分析
目的分析河南省1 287例新生儿泪囊炎病原菌分布及药敏结果。方法回顾性分析。收集2018年1月至12月该院1 287例泪囊素的病原菌培养及药敏结果。结果共检出病原菌1 099株,检出率为85.4%。革兰氏阳性菌618株(56.2%),其中金黄色葡萄球菌(19.3%)、表皮葡萄球菌(17.5%)、变形链球菌(10.4%)。革兰氏阴性菌458株(41.7%),其中流感嗜血杆菌(17.0%)、大肠杆菌(11.5%)、肺炎克雷伯菌(7.4%)。共有23株真菌(2.1%)。革兰氏阳性菌对万古霉素最敏感(98.8%),其次为左氧氟沙星(92.4%)。革兰氏阴性菌对亚胺培南最敏感(96.1%),其次为环丙沙星(91.4%)。革兰氏阳性菌和革兰氏阴性菌对红霉素耐药率最高。结论新生儿泪囊炎病原菌中革兰氏阳性菌多于革兰氏阴性菌。关键词:泪囊炎;新生儿;细菌致病性;敏感性,药物
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