Perfil lipídico en pacientes HIV positivos con dos tratamientos antirretrovirales que acudieron al Programa Regional de control VIH- SIDA de la VII Región Sanitaria de Itapúa en el periodo abril a septiembre de 2016

Abstract

Numerous research studies show that there is an impaired lipid metabolism in patients with HIV/AIDS, characterized by an increase in triglyceride concentration and decreased high- and low-density lipoproteins and total cholesterol. Dyslipidemia in HIV/AIDS people depends on viral suppression at the time of the study, response to the specific antiretroviral agent that relates to genetic susceptibility, as well as other factors including the use of medications, weight and lifestyle. Therefore, patients living with this infection have an increased risk of cardiovascular accident and diabetes. The objective was to determine whether there were differences in lipid profile in a cohort of patients receiving different treatment schemes in the targeted population. This was a prospective cohort design research with analytical component that included patients with HIV diagnosis and treatment that attended the Regional HIV-AIDS Control Programme at the Regional Hospital of Encarnacion - VII Itapua Health Region from April to September 2016. Significant differences were found in most analytes components of the lipid profile. A periodic control of the lipid profile is necessary in these patient groups as this will contribute to a better monitoring of the health status as well as to the prevention of cardiovascular accidents in patients living with HIV/AIDS, and who are being treated with antiretrovirals