{"title":"Diagnóstico y manejo del paciente adulto con diabetes tipo 1A al inicio de la enfermedad","authors":"Enric Serra, Elena Guanyabens, Eva Aguilera","doi":"10.1016/j.avdiab.2013.01.001","DOIUrl":null,"url":null,"abstract":"<div><p>Type 1 diabetes mellitus is a chronic, autoimmune disease, where specific pancreatic β-cell destruction leads to complete insulin deficiency.</p><p>Management of the patient at diagnosis includes patient education (training in insulin self-injection, self-monitoring of glucose and ketone levels, prevention and management of hypoglycaemia…) and intensive insulin treatment, aimed at achieving glucose concentrations as close to normal as safely possible and avoiding hypoglycaemia. Screening for associated thyroid and coeliac diseases is recommended at the onset of type<!--> <!-->1 diabetes. Pancreatic auto-antibody measurement, however, is only recommended in case of diagnostic uncertainly. The measurement of stimulated C-peptide after a mixed meal is the reference method to assess endogenous insulin production, although its use is currently limited to intervention trials.</p></div>","PeriodicalId":100152,"journal":{"name":"Avances en Diabetología","volume":"29 2","pages":"Pages 36-43"},"PeriodicalIF":0.0000,"publicationDate":"2013-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.avdiab.2013.01.001","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Avances en Diabetología","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1134323013000021","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 1
Abstract
Type 1 diabetes mellitus is a chronic, autoimmune disease, where specific pancreatic β-cell destruction leads to complete insulin deficiency.
Management of the patient at diagnosis includes patient education (training in insulin self-injection, self-monitoring of glucose and ketone levels, prevention and management of hypoglycaemia…) and intensive insulin treatment, aimed at achieving glucose concentrations as close to normal as safely possible and avoiding hypoglycaemia. Screening for associated thyroid and coeliac diseases is recommended at the onset of type 1 diabetes. Pancreatic auto-antibody measurement, however, is only recommended in case of diagnostic uncertainly. The measurement of stimulated C-peptide after a mixed meal is the reference method to assess endogenous insulin production, although its use is currently limited to intervention trials.
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