The potential mechanism of ubiquitin-proteasome system in non-small cell lung cancer

Abstract

The ubiquitin-proteinasome system (UPS) is a complex control system responsible for the degradation of 80%-90% of proteins and is the key to regulating cellular function and maintaining protein homology.Studies have shown that it plays an important role in the development of a variety of tumors.Therefore, the component of UPS has attracted extensive attention as a potential target for the diagnosis and treatment of lung cancer in recent years.This article reviews the research status of UPS in non-small cell lung cancer and its potential mechanism in the development of non-small cell lung cancer. Key words: Carcinoma, non-small-cell lung; Ubquitin-proteinasome system; Mechanism