Haemodynamic Changes & Complications between Unilateral and Bilateral Spinal Anesthesia in Elderly Type-2 Diabetic Patient Undergoing Hemiarthoplasty – A Comparative Study

Ferdous Ali, I. Khalilullah, A. Jabbar, M. Hasan, M. Rahman
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Abstract

Background: During spinal anesthesia, extend of sympathetic blockade causes hemodynamic instability,such as hypotension and bradycardia.It can lead to develop cardiac arrest in some cases. Elderly patientdo not compensate these haemodynamic change easily because of aging process leads some physiologicalchanges in all system especially on cardio vascular system e.g; decreased elasticity of vessels, decreasedvascular and myocardial compliance and also decreased autonomic responsiveness. It is hypothesizedthat unilateral spinal anesthesia restrict the spread of hyperbaric bupivacaine to one side only (dependentside) thus sparing the opposite sympathetic chain and hence would cause less haemodynamic changes. Materials & Methods: This cross sectional study, took place in the department of Anaesthesiology andSICU, BIRDEM General Hospital, Shahbag, Dhaka. A total 60 elderly (age-60 to 80 years), ASA grade IIand III, type-2 Diabetic patients scheduled for hemiarthoplasty were enrolled in this study. Patients weredivided into two groups U & A, 30 patients in each. Subarachnoid (spinal) anaesthesia was performed inall patients with 0.5% hyperbaric bupivacaine intrathecally, at L3 - L4 interspinous spaces, with 25GQuinke’s spinal needle. Patients of group U were kept in lateral decubitus position which was maintainedfor 15 minutes after injecting bupivacaine and patients of group B were kept in supine position. Changesof BP, pulse and development of any complication was recorded in 5 minute interval after spinal anesthesia.All the informations were recorded in preformed data collection sheet. Result: Compared with group U, group B showed statistically significant increase inheart rate at 10 minafter spinal anesthesia (p<0.05).Systolic BP was significantly lower in group B compared to group U in allrecorded time interval except at 60 minute.Diastolic blood pressure was significantly lower in group Bcompared to group U at 15, 30 and 45 minute reading. Regarding maen arterial pressure we found it wasreduced significantly in group B compared to group U in all the recorded time except at 60 minute(p<0.05). Present study showed none of the patients in the unilateral group experienced vomiting; onlytwo patients noticed nausea. In the bilateral group, seven patients had nausea and three of them experiencedepisodes of vomiting (p = 0.02). In group U, no case found hypotensive, only single developed bradycardia.In Group B 7 patients experienced hypotensions and 4 patients had bradycardia. Conclusion: This study showed that the unilateral spinal anesthesia reduces the incidence and severityof hypotension, bradycardia and other complication in elderly type-2 diabetic patients. So unilateralspinal anaesthesia is more benifecial for elderly type-2 diabetic patient in hemiarthoplasty. JBSA 2020; 33(2): 62-68
老年2型糖尿病患者行半胸骨成形术时单侧和双侧脊髓麻醉的血流动力学变化及并发症的比较研究
背景:在脊髓麻醉过程中,交感神经阻滞的延长引起血流动力学不稳定,如低血压和心动过缓。在某些情况下,它会导致心脏骤停。老年患者不容易补偿这些血流动力学变化,因为衰老过程会导致各系统特别是心血管系统的一些生理变化。血管弹性降低,血管和心肌顺应性降低,自主神经反应性降低。假设单侧脊髓麻醉限制高压布比卡因仅向一侧(依赖侧)扩散,从而保留对面的交感神经链,从而减少血流动力学变化。材料与方法:本横断面研究在达卡Shahbag BIRDEM综合医院麻醉科和sicu进行。本研究共纳入60例老年人(60 ~ 80岁),ASA分级为ii级和III级,2型糖尿病患者,计划行半关节成形术。将患者分为U组和A组,每组30例。所有患者均行蛛网膜下(脊髓)麻醉,在L3 - L4棘间间隙行0.5%高压布比卡因鞘内麻醉,使用25GQuinke脊髓针。U组患者注射布比卡因后保持侧卧位15分钟,B组患者保持仰卧位。每隔5分钟记录血压、脉搏变化及并发症发生情况。所有信息都记录在预先制作的数据收集表上。结果:与U组比较,B组脊髓麻醉后10min心率升高有统计学意义(p<0.05)。除60分钟外,B组的收缩压均明显低于U组。在15、30和45分钟读数时,b组的舒张压明显低于U组。除60分钟外,B组男性动脉压在所有记录时间内均明显低于U组(p<0.05)。目前的研究显示,单侧组没有患者出现呕吐;只有两名患者感到恶心。在双侧组中,7例患者出现恶心,其中3例出现呕吐(p = 0.02)。U组无一例出现低血压,仅有一例出现心动过缓。B组7例出现低血压,4例出现心动过缓。结论:本研究显示单侧脊髓麻醉可降低老年2型糖尿病患者低血压、心动过缓等并发症的发生率和严重程度。因此单侧脊髓麻醉对老年2型糖尿病患者进行半关节成形术更为有利。JBSA 2020;33 (2): 62 - 68
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