A study of serum zinc levels in children admitted with pneumonia in a tertiary care hospital in India

Ashrin A Naushad, L. Kailas, Sreekanth K Sivaraman
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引用次数: 1

Abstract

Background: Worldwide, pneumonia is a leading cause of morbidity and mortality in children under 5 years of age; especially, in developing countries. Objectives: The objective of the study is to investigate whether zinc deficiency and other nutritional factors are related to pneumonia in children between 6 months and 5 years old. Methodology: In this casecontrol study, a valid written consent was obtained from mothers of enrolled children. The cases included 75 children fulfilling the World Health Organization criteria for pneumonia, between the age group of 6 months and 5 years. They were interrogated for potential nutritional risk factors as per a predesigned proforma followed by a measurement of serum zinc levels. In the control group, 75 children of the same age group who were siblings of admitted children were included along with other children of the same age group admitted for non-respiratory complaints. A detailed case history was obtained and physical examination was done according to a predesigned proforma to elicit various potential risk factors. A semi-auto analyzer was used to measure the serum zinc levels through colorimetric methods using 5-bromo-PAS. Results: Significant nutritional risk factors identified were low serum zinc level, malnutrition, and anemia. Conclusion: The present study has identified various nutritional risk factors for pneumonia which can be tackled through effective education of the community and appropriate initiatives.
印度三级医院肺炎入院儿童血清锌水平的研究
背景:在世界范围内,肺炎是5岁以下儿童发病和死亡的主要原因;特别是在发展中国家。目的:本研究的目的是调查锌缺乏和其他营养因素是否与6个月至5岁儿童肺炎有关。方法学:在本病例对照研究中,从入组儿童的母亲那里获得了有效的书面同意。这些病例包括75名符合世界卫生组织肺炎标准的儿童,年龄在6个月至5岁之间。他们被询问潜在的营养风险因素,按照预先设计的形式,随后测量血清锌水平。在对照组中,75名同年龄组的儿童,他们是入院儿童的兄弟姐妹,与其他因非呼吸系统疾病入院的同年龄组儿童一起被纳入。获得详细的病例病史,并根据预先设计的形式进行体格检查,以得出各种潜在的危险因素。采用半自动分析仪,采用5-溴- pas比色法测定血清锌水平。结果:血清锌水平低、营养不良和贫血是显著的营养危险因素。结论:本研究确定了肺炎的各种营养危险因素,可通过有效的社区教育和适当的措施加以解决。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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