Generating the Responses Immune with Honey, Saussurea costus, and Nigella Sativa in Cellular and Humoral May Resolve COVID-19?

S. Prawiro, K. Anam, Bobi Prabowo, R. Bramanthi, Avin Ainur Fitrianingsih, D. Hidayati, Siwipeni Imawati, Etty Fitria, S. Winarsih
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引用次数: 3

Abstract

Backgrounds: Covid-19 has become pandemic in the world, including Indonesia. Some Indonesia Covid-19 people tried to consume Honey, Sausseria coctus, and Nigella sativa for curing the Covid-19 disease. From many testimonies, citizen Indonesia people with no need to take hospitalization have reported a cure if they consumed it. Aims: To make evidence-based medicine that Honey, Sausseria coctus dan Nigella may cure the Covid-19 Methods: We used to post only control design and mice as an animal model. The research divided mice into two groups, and the first group as control received PBS as a placebo. Then the second group, we gave Honey, Sausseria coctus dan Nigella sativa. All of the regiment enters the mouth with special sonde to reach the gastrointestinal organ. After administration regiments a long three weeks, we sacrificed the mice. We evaluated cellular immune responses that are Th2, Th17, and NK cells. We check for humoral immune response, TGF-β, IL-17A, sIgA, IL-4, IL-4, B-def, and IgG. Results: We got deference Th2 and Th17 between control with treatment group (p=0.05). For markers, humoral immunity all has deference between control with treatment group (p=>0.05) statistically, but one (IL-17A) have no statistical difference. Conclusions: We want to continue studying immune responses in humans with COVID-19 if giving Honey, Sausseria coctus, and Nigella sativa.
蜂蜜、雪莲和黑草在细胞和体液中产生免疫反应可以解决COVID-19?
背景:新冠肺炎疫情已成为包括印尼在内的全球大流行疫情。一些印度尼西亚Covid-19患者试图通过食用蜂蜜、球菌索氏菌和黑籽来治疗Covid-19疾病。从许多证词来看,不需要住院的印度尼西亚公民报告说,如果他们食用它,就可以治愈。目的:研究蜂蜜、奈氏球菌治疗新冠肺炎的循证医学方法:采用单纯对照设计,以小鼠为动物模型。该研究将小鼠分为两组,第一组作为对照组接受PBS作为安慰剂。然后第二组,我们给蜂蜜,球菌和黑孢杆菌。所有的人都带着特殊的探头进入口腔,到达胃肠道器官。在给药团长达三周后,我们将小鼠处死。我们评估了Th2、Th17和NK细胞的细胞免疫反应。我们检测体液免疫应答、TGF-β、IL-17A、sIgA、IL-4、IL-4、B-def和IgG。结果:对照组与治疗组Th2、Th17差异有统计学意义(p=0.05)。在体液免疫指标方面,对照组与治疗组差异均有统计学意义(p=>0.05),但有一项指标IL-17A差异无统计学意义。结论:我们希望继续研究给予蜂蜜、球菌索氏菌和黑孢菌的COVID-19患者的免疫反应。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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