A study of serum magnesium level in critically ill patients

Prasad G Ugaragol, L. S. Patil, Deepak Chinagi
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Abstract

Background: It is considered that Hypomagnesemia is one of the underdiagnosed electrolyte abnormalities in patients who are critically ill. Many studies have been done to find the hypomagnesemia prevalence and its effects on patients regarding mortality and morbidity. So we have undertaken this study to know the effects of Hypomagnesemia in critically ill patients admitted in medical critical ward. And it is an observational study. Aims and Objectives: To study the level of serum magnesium in critically ill patients and to correlate its effects with patient outcome in terms of length of stay in ICU, need for ventilator support, duration of ventilator support, APACHE II score. To detect any electrolyte abnormalities associated with hypomagnesemia. Results: In our study, on admission in ICU, 55.3% patients had hypomagnesemia, and patients with hypomagnesemia have mean duration of stay in ICU was 8.2 days, longer duration on mechanical ventilator i.e. 6.3 day and APACHE II Score of 15.7 and more frequently patients were in sepsis (25.9%), 15.3 % had cardiovascular abnormality. Patients with hypomagnesemia were more frequently associated with Diabetes Mellitus (34%) and they were having higher mortality rate (48.9%). Conclusion: In the critically ill patients Hypomagnesemia was prevalent in higher rate. And it was associated with a higher mortality rate in them. And the requirement of ventilator support and duration on ventilator was significantly higher in hypomagnesemic patients. Hypomagnesemia was more commonly associated with sepsis, diabetes mellitus. And also it was associated with higher mortality rates and APACHE II Score.
危重病人血清镁水平的研究
背景:低镁血症被认为是危重患者电解质异常的漏诊之一。关于低镁血症的患病率及其对患者死亡率和发病率的影响,已经进行了许多研究。因此,我们开展了这项研究,以了解低镁血症对住院危重病人的影响。这是一项观察性研究。目的和目的:研究危重患者血清镁水平及其与ICU住院时间、呼吸机支持需求、呼吸机支持持续时间、APACHEⅱ评分的相关性。检测与低镁血症相关的电解质异常。结果:本组患者入ICU时低镁血症发生率为55.3%,低镁血症患者平均住院时间为8.2天,机械呼吸机使用时间较长,为6.3天,APACHEⅱ评分为15.7,脓毒症发生率较高(25.9%),心血管异常发生率为15.3%。低镁血症患者常伴有糖尿病(34%),且死亡率较高(48.9%)。结论:危重症患者低镁血症发生率较高。这与他们较高的死亡率有关。低镁血症患者对呼吸机支持的需求和使用呼吸机的时间明显高于低镁血症患者。低镁血症多与败血症、糖尿病相关。它也与更高的死亡率和APACHE II评分有关。
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