Endovascular embolization with Onyx of spinal metastases from renal cell carcinoma

Daniel López , Elvira Jiménez Gómez , María José Méndez Vidal , Rafael Oteros Fernández , Fernando Delgado Acosta
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Abstract

Bone metastases occur in 50% of patients with renal cell carcinoma, approximately 15% of these occur in the spine. In patients with disseminated disease with osseous metastases in vertebral bodies without options for curative treatment, cement injection in the vertebrae can be a useful tool in the management of pathologic fractures by allowing stabilization of the spine and ameliorating pain.

A potential contraindication to this procedure is posterior vertebral wall involvement due to increased risk of cement leakage into the epidural space. In some of these cases, embolization with PVA particles and/or surgery is necessary.

We present a case of lumbar spine metastases from renal cell carcinoma, with posterior wall involvement, that was treated by endovascular embolization using Onyx polymer. To the best of our knowledge, embolization of this kind of lesion, using this embolic agent, has not been previously reported.

肾细胞癌脊柱转移瘤的血管内栓塞治疗
50%的肾细胞癌患者发生骨转移,其中约15%发生在脊柱。对于弥散性疾病伴椎体骨转移而无治愈治疗选择的患者,椎体骨水泥注射可成为治疗病理性骨折的有效工具,可使脊柱稳定并减轻疼痛。该手术的潜在禁忌症是由于水泥渗漏到硬膜外腔的风险增加而累及后椎壁。在某些情况下,PVA颗粒栓塞和/或手术是必要的。我们报告一例腰椎肾细胞癌转移,并累及后壁,我们使用Onyx聚合物进行血管内栓塞治疗。据我们所知,这种病变的栓塞,使用这种栓塞剂,以前没有报道过。
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