Acute Fatty Liver of Pregnancy: A Life Threatening Condition

Sarita Sitaula, A. Agrawal, A. Thakur, T. Manandhar, Babauram Dixit Thapa, Jibanath Dhamala
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Abstract

Acute Fatty Liver of Pregnancy (AFLP) is a rare but catastrophic disease affecting women in pregnancy. It usually occurs in the third trimester or post-partum period. Delay in diagnosis is associated with morbid complications with high morbidity and mortality. We report a case of 24 years old female at 38 weeks period of gestation who presented with jaundice, vomiting for 3 days and deranged liver function test. She was diagnosed as acute fatty liver of pregnancy and was delivered by instrumental delivery but required cesarean hysterectomy due to postpartum hemorrhage. She started improving with supportive care and discharged after 4 weeks of hospital stay.
妊娠期急性脂肪肝:一种危及生命的疾病
急性妊娠脂肪肝(AFLP)是一种罕见但严重影响妊娠妇女的疾病。它通常发生在妊娠晚期或产后。诊断延误与高发病率和高死亡率的病态并发症有关。我们报告一例24岁女性,孕38周时出现黄疸,呕吐3天,肝功能检查紊乱。她被诊断为急性妊娠脂肪肝,通过器械分娩,但由于产后出血需要剖宫产子宫切除术。患者在支持性护理下开始好转,住院4周后出院。
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