Analysis of spirometric variables with increasing body mass index in normal and overweight healthy individuals

IF 0.2 Q4 MEDICINE, GENERAL & INTERNAL
Ilham Jaleel, H. Ahamed
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引用次数: 0

Abstract

Background: The relationship between the parameters of body mass index (BMI) and lung function has been established by numerous studies done earlier. Those studies have been done mainly on obese individuals, but only a very few studies have been done in people with normal BMI or overweight group. Our aim is to analyze the various spirometric variables, namely forced expiratory volume in 1 s (FEV1), forced vital capacity (FVC), forced expiratory flow (FEF 25%–75%), and peak expiratory flow rate (PEFR), with respect to increase in the BMI in otherwise normal healthy subjects. Methods: The present study design is a randomized experimental parallel-group study. Sixty individuals who were otherwise healthy without any respiratory illness were selected for this study. Their anthropometric measurements were taken. Based on WHO classification, the subjects were grouped as follows: Group I with a BMI of 18.5–24.9 as a normal weight group and Group II with a BMI of 25–29.9 as the overweight group. Using Medispiror, the spirometric variables were determined. Analysis of spirometric variables, namely FEV1, FVC, FEF 25%–75%, and PEFR, were all done using the appropriate statistical method. Results: The results showed that there was a significant decrease in all spirometric variables except PEFR with an increase in BMI. However, the decrease in FVC was relatively more than the decrease in FEV1. Conclusion: This study can be concluded that there is a significant decrease in spirometric variables, namely FEV1, FVC, and FEF 25%–75%, as the BMI increases even in normal individuals who are not obese.
正常和超重健康人体重指数增加对肺活量测量变量的影响分析
背景:身体质量指数(BMI)参数与肺功能之间的关系已被早期的大量研究所确立。这些研究主要是针对肥胖人群进行的,但只有很少的研究是针对BMI正常或超重人群进行的。我们的目的是分析各种肺活量测量变量,即1秒内用力呼气量(FEV1)、用力肺活量(FVC)、用力呼气流量(FEF 25%-75%)和呼气峰值流量(PEFR)与正常健康受试者BMI增加的关系。方法:本研究设计为随机实验平行组研究。60名没有任何呼吸系统疾病的健康个体被选为这项研究的参与者。对他们进行了人体测量。根据WHO的分类,受试者分为:BMI为18.5-24.9的I组为正常体重组,BMI为25-29.9的II组为超重组。使用Medispiror测定肺活量变量。肺活量测定变量FEV1、FVC、FEF 25% ~ 75%、PEFR均采用相应的统计学方法进行分析。结果:结果显示,除PEFR外,所有肺量指标均随BMI升高而显著降低。但FVC的下降相对大于FEV1的下降。结论:本研究可以得出结论,即使在非肥胖的正常个体中,随着BMI的增加,肺活量指标FEV1、FVC、FEF也显著降低25%-75%。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Journal of Clinical Sciences
Journal of Clinical Sciences MEDICINE, GENERAL & INTERNAL-
自引率
0.00%
发文量
15
审稿时长
45 weeks
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