Comparison of Risk Scores for the Prediction of Outcomes after Surgery for Acute Type A Aortic Dissection

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Abstract

We compared the performance of four existing risk models and a newly developed risk score for type A acute aortic dissection surgery. In 327 consecutives with type A aortic dissection surgery patients during 2003/03-2017/03 at our centre, operative mortality occurred in 65 (19.9%). Independent predictors of operative mortality were critical pre-operative state and malperfusion syndrome, and a novel additive “CritMal” Score was constructed from this. C-statistics (95% confidence interval) for operative mortality were EuroSCORE 0.60 (0.52-0.67), EuroSCORE II 0.64 (0.57-0.72), Rampoldi 0.68 (0.59-0.76), Leontyev 0.56 (0.48-0.64), and CritMal 0.72 (0.64-0.80) respectively. This is the first study externally assessing surgical scores for aortic dissection surgery, with modest accuracy for all and moderate for CritMal. There is room for improvement of these risk models, and further refinements and external validation are warranted for clinical application.
急性A型主动脉夹层术后预后的风险评分比较
我们比较了四种现有风险模型和新开发的a型急性主动脉夹层手术风险评分的表现。2003/03-2017/03年在我院连续327例A型主动脉夹层手术患者中,65例(19.9%)发生手术死亡率。手术死亡率的独立预测因子是临界术前状态和灌注不良综合征,并由此构建了一种新的附加性“临界”评分。手术死亡率的c -统计值(95%可信区间)分别为EuroSCORE 0.60(0.52-0.67)、EuroSCORE II 0.64(0.57-0.72)、Rampoldi 0.68(0.59-0.76)、Leontyev 0.56(0.48-0.64)、CritMal 0.72(0.64-0.80)。这是第一个对主动脉夹层手术评分进行外部评估的研究,对所有人的准确性中等,对CritMal的准确性中等。这些风险模型还有改进的空间,临床应用需要进一步的改进和外部验证。
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