Strategies for the Microbiological Testing of Cosmetic Gels

Q. Shaqra, A. Q. A. Shaqra, Mohammad Q. Abu Shaqra
{"title":"Strategies for the Microbiological Testing of Cosmetic Gels","authors":"Q. Shaqra, A. Q. A. Shaqra, Mohammad Q. Abu Shaqra","doi":"10.9734/BJPR/2016/25196","DOIUrl":null,"url":null,"abstract":"Background: Official methods for the microbiological testing of cosmetics are available; evidence is required for the suitability of procedure employed particularly while dealing with thick or viscous preparations such as gel formulations. Aim: To illustrate the inherent problems that exist in conventional methodologies used for the microbiological testing of cosmetic gels and to recommend new strategies which could yield more consistent results. Place and Duration of Study: The work was carried out at the quality control laboratories in Jordan Medical Solutions Manufacturing Company over a period of 4 months Methodology: A carbomer based hair styling gel formulation and a cell suspension of Pseudomonas aeruginosa ATCC 9027 were prepared following standard procedures. Homogeneous dispersion of the prepared microbial challenge into the gel was achieved by two approaches. The first depended on inoculating the gel preparation prior to the addition of alkali while the second relied on breaking down the gel matrix by acidification of the original gel to pH 4","PeriodicalId":9320,"journal":{"name":"British journal of pharmaceutical research","volume":"13 1","pages":"1-6"},"PeriodicalIF":0.0000,"publicationDate":"2016-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"British journal of pharmaceutical research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.9734/BJPR/2016/25196","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

Abstract

Background: Official methods for the microbiological testing of cosmetics are available; evidence is required for the suitability of procedure employed particularly while dealing with thick or viscous preparations such as gel formulations. Aim: To illustrate the inherent problems that exist in conventional methodologies used for the microbiological testing of cosmetic gels and to recommend new strategies which could yield more consistent results. Place and Duration of Study: The work was carried out at the quality control laboratories in Jordan Medical Solutions Manufacturing Company over a period of 4 months Methodology: A carbomer based hair styling gel formulation and a cell suspension of Pseudomonas aeruginosa ATCC 9027 were prepared following standard procedures. Homogeneous dispersion of the prepared microbial challenge into the gel was achieved by two approaches. The first depended on inoculating the gel preparation prior to the addition of alkali while the second relied on breaking down the gel matrix by acidification of the original gel to pH 4
化妆品凝胶的微生物检测策略
背景:化妆品微生物检测的官方方法是可用的;特别是在处理粘稠或粘性制剂(如凝胶制剂)时,需要证据来证明所采用程序的适用性。目的:阐明化妆品凝胶微生物检测的传统方法中存在的固有问题,并建议可以产生更一致结果的新策略。研究地点和时间:这项工作在约旦医疗解决方案制造公司的质量控制实验室进行,为期4个月。方法:按照标准程序制备卡波默基发胶配方和铜绿假单胞菌ATCC 9027细胞悬浮液。制备的微生物挑战剂通过两种方法均匀分散到凝胶中。第一种方法是在加入碱之前接种凝胶制剂,第二种方法是通过将原始凝胶酸化至pH 4来分解凝胶基质
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信