Fast-track Surgery Protocol for Hepatectomy and the Rate of Surgical Site Infections: A Single-center Study

Abstract

: The fast-track surgery protocol, including perioperative immunonutritional management, is increasingly gaining attention for the prevention of surgical site infections （ SSIs ） . To analyze the association between the fast-track surgery protocol employed at a single center and outcomes, including SSIs and the length of hospital stays. This retrospective analysis included 217 patients who underwent hepatectomy at the study department between January 2009 and February 2014. Patients were divided into two groups : those managed by a conventional protocol （ group C, n ＝ 75 ） and those managed by the fast-track surgery protocol （ group F, n ＝ 142 ） . There were no significant differences in patient characteristics or factors between the two groups. and total cholesterol levels surgery were significantly higher in group F than in group C, and pre-hepatectomy C-reactive protein （ CRP ） levels were lower in group F than in group C. serum CRP The operations group F than in group C （ 312 vs. 286 min ） and blood loss volume was less （ 385 g group F vs. 428 ） . SSI in group F （ 4.2 ％ , n ＝ ） C , , F （ days C （ 25.8 fast-track surgery perioperative strategy may improve preoperative nutritional status and postoperative inflammation, with subsequent reductions in SSI rates and the length of hospital stay in patients undergoing hepatectomy.