EVALUATION OF HOMOCYSTEINE AND VITAMIN D LEVELS IN OSTEOARTHRITIS PATIENTS

Abstract

In this study, we aimed to investigate whether there is a change in the levels of vitamin D, vitamin B12, folic acid, which are important for metabolism, and homocysteine levels, which are considered to be an indicator of oxidative stress, in women with osteoarthritis. This study was conducted on 30 women with osteoarthritis (Group I) and 30 healthy women (Group II) who applied to the orthopedic outpatient clinic in Kahramanmaras Necip Fazil City Hospital between January and December 2020. Plasma homocysteine, serum folic acid, vitamin B12 and vitamin D levels were evaluated in the study. In homocysteine levels; a statistically significant increase was found in the group with osteoarthritis (Group I) (p<0.05). In folic acid, vitamin B12, vitamin D levels; a statistically significant decrease was detected in the group with osteoarthritis (Group I) (p<0.05). In conclusion, we think that folic acid, which provide homocysteine excretion; vitamin B12 and vitamin D levels that contribute to the development of OA should be followed up and added to the diet in case of deficiency in patients with OA or joint disease that reduce the quality of life.