The study of the antibacterial and antimycotic activity of nanostructures based on antibiotics, plant extracts and salts metals

Abstract

The antibacterial activity of nanostructures based on antibiotics, plant extracts and metal salts against Escherichia.coli, Staphylococcus sp. and Aspergillus niger was shown. A statistically significant increase in the inhibition effect of ceftriaxone in the poludan was shown by 33,3%, copper sulfate in Na-CMC by 121,5-562,7% depending on the ratio of core:shell and suspension concentration, birch leaf extract in Na-alginate by 36,7-86,3%, in guar gum by 110,0484,5% compared with pure preparations. The inhibitory effect from nanostructured silver nitrate was not detected. The most effective ratios are core:shell 1:1 and 1:2. Keywords—nanostructured forms; antibiotics; plant extracts; metal salts; biocidal activity