Studies on wound healing properties of Crateva religiosa leaf extract

U. Ajali, Km Ezealisiji, E. Onuoha
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引用次数: 6

Abstract

Dried leaves of Crateva religiosa were extracted with methanol using a soxhlet extractor. The classes of phytocompounds present in the extract were determined and the LD 50  estimated in mice intraperitoneally. The extraction gave a yield of 14.6%. Alkaloids, carbohydrates, tannins, flavonoids, resins, proteins, oils, steroids and terpenoids were present. The extract had wound healing activity that was superior to that of penicillin. The faces of wound treated with the extract dried faster indicating that the extract had extrawound healing mechanism when compared to that of penicillin. Keywords : Creteva religiosa , wound healing, phytochemisty, LD 50 Journal of Pharmaceutical and Allied Sciences , Vol. 7 No. 4 (2010)
山楂叶提取物创面愈合特性的研究
采用索氏提取器,以甲醇为溶剂,对山楂干叶进行了提取。测定了提取物中存在的植物化合物的种类,并估计了小鼠腹腔注射的ld50。提取得率为14.6%。生物碱、碳水化合物、单宁、黄酮类化合物、树脂、蛋白质、油脂、类固醇和萜类化合物。该提取物的创面愈合活性优于青霉素。与青霉素相比,该提取物处理的创面干燥速度更快,表明该提取物具有创面外愈合机制。关键词:白藜芦醇,伤口愈合,植物化学,LD 50药学与相关科学杂志,Vol. 7 No. 4 (2010)
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