Occurrence of mutations associated with rifampicin and isoniazid resistant in Mycobacterium tuberculosis isolates from patients in Burkina Faso

Abstract

The emergence of multidrug resistant (MDR) strains of MTBC has become one of the most critical issues for tuberculosis (TB) control programmes worldwide. It is a public health concern threatening global TB control programs. Its diagnosis has evolved in recent years following the development of new molecular techniques based on detection of mutations in MTBC genes by Polymerase Chain Reaction (PCR).1–3