Potential Reno-Protective Effects of Telmisartan in Kurd Non-Diabetic Hypertensive Patients in Hawler City

Abstract

Angiotensin II (AII) type I (AT1) receptor blockers are a well known group of drug that indicated principally for the treatment of hypertension as well as for the protection of kidney function in diabetic patients. Telmisartan is a highly selective angiotensin receptor blocker, and the favourable tolerability profile of telmisartan combined with its long elimination half- life ensure the drug provides pronounced reductions in blood pressure (BP) across the entire 24-hour dosage interval. There is relatively very little data and information available to reveal renoprotective activity of telmisartan in nondiabetic low grade albuminuric Kurd hypertensive patients. Our study explores the effect of telmisartan on mean arterial blood pressure and it also sheds more light on its crucial role in lowering albumin: creatinine ratio in Kurd patients. The results of our study demonstrate that telmisartan reduces mean arterial blood pressure significantly, furthermore the study had explained a significant reduction in albuminuria at the second month of treatment which is regarded as a positive sign of renoprotection.