The role of endoscopy in the evaluation and management of patients with suspected pancreatic malignancy

Todd H Baron MD , Shawn Mallery MD , Grace Elta MD (Editor)
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引用次数: 39

Abstract

Commentary

Pancreatic cancer is the second most frequent gastrointestinal malignancy with approximately 29,000 new cases occurring annually in the United States. Almost all of these patients will die from the disease, making pancreatic cancer the fourth leading cause of cancer death for both men and women. Since surgical resection of the tumor offers the only chance for a cure, modalities for early diagnosis and accurate preoperative staging have continued to evolve. In this review, Drs. Mallery and Baron discuss the role of new diagnostic modalities including helical or multi-detector CT scan, endoscopic ultrasound (EUS), EUS-guided fine needle aspirate, and MRI, MRCP, and MR angiography. ERCP is now primarily relegated to a therapeutic palliative role in inoperable patients. A clinical management algorithm for patients with suspected pancreatic cancer is provided.

内镜在疑似胰腺恶性肿瘤患者的评估和治疗中的作用
胰腺癌是第二大最常见的胃肠道恶性肿瘤,在美国每年约有29,000例新发病例。几乎所有这些患者都会死于这种疾病,使胰腺癌成为男性和女性癌症死亡的第四大原因。由于手术切除肿瘤提供了治愈的唯一机会,早期诊断和准确的术前分期的方式不断发展。在这篇综述中,dr。Mallery和Baron讨论了新的诊断方式的作用,包括螺旋或多探测器CT扫描、内镜超声(EUS)、EUS引导的细针抽吸、MRI、MRCP和MR血管造影。ERCP现在主要被降级为不能手术患者的治疗性姑息作用。提出了一种疑似胰腺癌患者的临床管理算法。
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