To compare limb strength, core strength, and respiratory endurance between post-COVID-19 and healthy population: A cross-sectional study

IF 0.2 Q4 PHARMACOLOGY & PHARMACY
Pardeep Pathak, Sunita Sharma, Nitin Gupta, Diggaj Shrestha, R. Bala, Raval Chinubhai
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Abstract

Background: Coronavirus disease (COVID-19) adversely affects the number of organs and systems of the human body. The most frequently affected organ is the lung, followed by skeletal muscles, which can lead to fatigue, weakness, and poor physical performance. Objective: The objective of this study was to compare the grip strength, core strength, 6-min walk test (6-MWT), and pulmonary function test (PFT) between healthy individuals and post-COVID-19 individuals. Methodology: A cross-sectional study was conducted for the comparison among the post-COVID-19 participants and the healthy ones. Their demographic characteristics were noted. We analyzed heart rate, oxygen saturation, and cardiac rhythm before and 10 min after the 6-MWT and also PFT, core strength, and hand grip strength. The correlations among the tests if any were noted. Results: Forty-six post-COVID-19 individuals and 44 healthy individuals were enrolled in the study. The mean age was 39.18 ± 13.12 years for healthy individuals and 37.28 ± 11.68 for post-COVID individuals with 62% of the female population. The mean distance for a 6-min walk distance was 506.68 ± 64.75 m for healthy individuals and 430.30 ± 52.96 for post-COVID-19 individuals (P < 0.000). The mean value for PFT was 85.59 ± 6.78 for healthy and 72.28 ± 6.20 for post-COVID individuals. We found a positive correlation between PFT with core endurance (P = 0.036) and hand strength (P = 0.037), core endurance with 6-MWT (P = 0.006) and hand strength (P = 0.00), and 6-MWT with hand strength (P ≤ 0.001) in post-COVID participants; whereas no correlation was found in healthy participants group. Conclusion: The PFT correlated significantly with core endurance and hand grip strength on post-COVID-19 individuals.
比较covid -19后和健康人群的肢体力量、核心力量和呼吸耐力:一项横断面研究
背景:冠状病毒病(COVID-19)对人体器官和系统的数量产生不利影响。最常受影响的器官是肺,其次是骨骼肌,这会导致疲劳、虚弱和身体表现不佳。目的:本研究的目的是比较健康个体和covid -19后个体的握力、核心力量、6分钟步行测试(6-MWT)和肺功能测试(PFT)。方法:采用横断面研究方法,将新冠肺炎后参与者与健康参与者进行比较。注意到它们的人口特征。我们分析了6-MWT前和10分钟后的心率、血氧饱和度和心律,以及PFT、核心力量和手握力。注意到测试之间的相关性。结果:46名covid -19后个体和44名健康个体入组研究。健康人群平均年龄39.18±13.12岁,感染后人群平均年龄37.28±11.68岁,女性占62%。健康人群步行6 min的平均距离为506.68±64.75 m,感染后人群步行6 min的平均距离为430.30±52.96 m (P < 0.000)。健康人PFT平均值为85.59±6.78,新冠病毒感染者PFT平均值为72.28±6.20。我们发现PFT与核心耐力(P = 0.036)和手部力量(P = 0.037)呈正相关,核心耐力与6-MWT (P = 0.006)和手部力量(P = 0.00)呈正相关,6-MWT与手部力量(P≤0.001)呈正相关;而在健康参与者组中没有发现相关性。结论:新冠肺炎患者PFT与核心耐力和手部握力显著相关。
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