Nevus Depigmentosus: a series with analysis of 37 cases.

Abstract

BACKGROUND Nevus depigmentosus (ND) is an uncommon congenital nonprogressive hypopigmented skin disorder that can be seen anywhere on the body. We consider other depigmenting disoders and focus on distinguishing ND from vitiligo and tuberous sclerosis complex in infancy. METHODS We evaluated patients with nevus depigmentosus. This diagnosis was made about delineating it from nevus anemicus, pityriasis alba, tuberous sclerosis complex, vitiligo, and other depigmenting disorders. RESULTS Of the 37 individuals with nevus depigmentosus evaluated, 36 were children, twenty-two (59.4%) were males and 15 (40.5%) were females, with male to female ratio 1.4:1. CONCLUSIONS Distinguishing ND from other disorders with depigmentation can be challenging, particular with tuberous sclerosis complex and vitiligo in infancy.