Design and Prototype Development of a Low-Cost Blood Flow Simulator for Vascular Phantoms

Matteo Zauli, C. Corsi, L. Marchi
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Abstract

Vascular phantoms can be used as in vitro test objects to explore flow behaviour in pathological conditions and novel ways of improving ultrasound diagnosis. This kind of phantom should be anatomically realistic both in terms of geometry, acoustic and physical properties. In particular, enhancing measurements reliability of in vitro models test needs a realistic physiological flow performed by a reliable phantom set-up.This paper describes the design of a programmable flow pump system, designed to be used in an in vitro experimental studies. This system wants to overcome budget problem due mainly to expensive flowmeters. The proposed solution is to use a low cost device, not able to perform a reliable closed loop control, but suitable to obtain an ARX non-linear model of the hydraulic circuit thanks to Matlab tools. By using that model, it is possible to act an open loop control able to produce the targeted waveform with median deviation less than 9% and a similarity index of 0.98.Here, we present also the flow rate calibration steps of the designed flow phantom set-up. In the current work, the flow pump system has been developed using Carotid artery Phantom (CaP), but thanks of its programmability it’s possible to implement different flow profiles suitable for others flow phantoms.
低成本血管幻象血流模拟器的设计与原型开发
血管幻影可以作为体外实验对象来探索病理状态下的血流行为和提高超声诊断的新方法。这种模型在几何、声学和物理特性上都应具有解剖学上的真实感。特别是,提高体外模型测试的测量可靠性需要一个可靠的模拟装置来实现真实的生理流动。本文介绍了一种可编程流量泵系统的设计,设计用于体外实验研究。该系统主要是为了克服流量计昂贵造成的预算问题。提出的解决方案是使用低成本的设备,不能进行可靠的闭环控制,但适合借助Matlab工具获得液压回路的ARX非线性模型。通过使用该模型,可以作为开环控制,能够产生中值偏差小于9%,相似指数为0.98的目标波形。本文还介绍了所设计的流模装置的流量标定步骤。在目前的工作中,流量泵系统是使用颈动脉幻像(CaP)开发的,但由于其可编程性,可以实现适用于其他流幻像的不同流量曲线。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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