Central Diabetes Insipidus Caused by Therapeutic Hypothermia after Cardiopulmonary Resuscitation with Carbon Monoxide Poisoning

Abstract

Central Diabetes Insipidus (DI) usually has hypernatremia and increased urine output as the main clinical manifestations. It is also a rare complication of therapeutic hypothermia after cardiopulmonary resuscitation and carbon monoxide poisoning, but it may be fatal if it is not recognized in time. This case describes a patient who experienced cardiac arrest due to carbon monoxide poisoning, and then successfully restored his spontaneous heart rate after cardiopulmonary resuscitation. However, the patient experienced unexpected hypernatremia and increased urine output during therapeutic hypothermia, and was diagnosed with central DI as a complication of cerebral edema. After treatment, he eventually developed spontaneous breathing and corrected electrolyte imbalances.Central DI should be taken seriously as a possible complication of increased urine output during therapeutic hypothermia after carbon monoxide poisoning cardiopulmonary resuscitation, and pituitary vasopressin should be used to treat central DI.