Role of Fibrin Glue in palatoplasty to prevent formation of oro-nasal fistula – An in vivo study

Abstract

Objective

To decrease the incidence of oro-nasal fistula formation following palatoplasty using modified Von Langenbeck technique and Fibrin Glue adhesive between the oral and nasal layer.

Subjects and methods

Prospective study of 20 primary closure of cleft palate using modified Von Langenbeck technique with and without a adhesive medium between the oral and nasal layer to compare the incidence of oro-nasal fistula formation.

Results

The results showed decrease in the incidence of oro-nasal fistula formation. With 0% fistula formation in the cases where Fibrin Glue was used. And 30% fistula formation in patients/controls where Fibrin Glue was not used.