Effect of fluoride- and nonfluoride-remineralizing agents in white spot lesions in mentally retarded children: A parallel randomized clinical trial

Abstract

Background: Dental caries is one of the prevalent oral diseases among mentally retarded children, and restorative, preventive treatment needs are unmet. Materials and Methods: The study was a double-blinded, parallel, randomized clinical trial. A total of 150 participants aged 7–12 years were selected. Unpaired t-test and repeated measures analysis of variance test were used for analysis. Results: In Group A, at 12 months, 97.2% active and 2.8% inactive lesions were reported. In Group B, at 9 and 12 months, 98.6% and 94.3% active and 1.4% and 5.7% inactive white spot lesions (WSLs) were seen. Conclusion: Fluoride- and nonfluoride-remineralizing agents reported a slight reduction in active WSLs.