A Histomorphology Comparison of Saw-Tooth Shaped Rete Ridge Between Oral and Cutaneous Lichen Planus

Arezoo Saharkhiz, A. Aminzadeh, Roya Yahyaabady
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Abstract

Lichen planus is chronic and comparatively collective inflammatory mucocutaneous disease. The histopathological features of oral lichen planus were described as comparable to those of cutaneous lichen planus(CLP). Among those saw-toothed rete ridges are introduced as less important histopathologic features of idiopathic OLP in contrast to CLP. Accordingly, existing study aimed to estimate existence of saw tooth rete ridges in OLP in comparison to CLP.; In this retrospective cross-sectional study, 56; E stained slides with clinical and histopathological diagnoses of OLP were randomly collected from the archive of the oral pathology laboratory. CLP cases were selected randomly from a private pathology laboratory and were evaluated for the presence of saw-toothed rete ridges. Collected data were evaluated using Chi-square; Fishers exact test in SPSS 24 at an error level of 0.05%. Chi-square test did not show a substantial difference between oral; cutaneous groups in terms of the shape of the rete ridges (p = 0.511). Outcomes of existing study showed that saw tooth rete ridge was seen in OLP similar to CLP. Future studies concerning clinical subtype and type of keratosis are recommended.
口腔扁平苔藓与皮肤扁平苔藓锯齿状嵴的组织形态学比较
扁平苔藓是一种慢性、群体性炎症性粘膜皮肤病。口腔扁平苔藓的组织病理学特征与皮肤扁平苔藓(CLP)相当。在这些锯齿状的网状隆起中,与CLP相比,特发性OLP的组织病理学特征不太重要。因此,现有的研究旨在估计与CLP相比,OLP中锯齿状网状脊的存在;在这项回顾性横断面研究中,56;随机从口腔病理实验室的档案中收集临床和组织病理学诊断为OLP的E染色玻片。从一个私人病理实验室随机选择CLP病例,并评估是否存在锯齿状的网状脊。收集的资料采用卡方法进行评价;fisher在SPSS 24中精确检验,误差水平为0.05%。卡方检验未显示口服;皮肤组在皮肤脊的形状方面(p = 0.511)。现有研究结果显示,OLP与CLP相似,可见锯齿状网状嵴。建议对角化病的临床亚型和类型进行进一步的研究。
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